Ten-minute consult

1. A journal club reviews rapid strep antigen versus culture. The 2×2 counts are true positives 21, false positives 9, false negatives 6, true negatives 84. What is the PPV (nearest value among the options)? The most appropriate action is: 70.0%

2. A journal club reviews D-dimer versus imaging-proven VTE in a selected GP cohort. The 2×2 counts are true positives 40, false positives 60, false negatives 10, true negatives 90. What is the sensitivity (nearest value among the options)?

3. A journal club reviews spirometry obstruction versus specialist confirmation. The 2×2 counts are true positives 90, false positives 30, false negatives 10, true negatives 70. What is the NPV (nearest value among the options)? The most appropriate action is: 90.0%

4. A journal club reviews urinary antigen versus legionella culture. The 2×2 counts are true positives 12, false positives 3, false negatives 8, true negatives 177. What is the specificity (nearest value among the options)? The most appropriate action is: 60.0%

5. A journal club reviews PSA cut-off versus biopsy cancer in a referred cohort. The 2×2 counts are true positives 15, false positives 35, false negatives 5, true negatives 145. What is the sensitivity (nearest value among the options)?

6. A journal club reviews HbA1c threshold versus OGTT diabetes. The 2×2 counts are true positives 36, false positives 18, false negatives 4, true negatives 142. What is the PPV (nearest value among the options)? The most appropriate action is: 66.7%

7. A journal club reviews urinalysis nitrite versus culture UTI. The 2×2 counts are true positives 41, false positives 9, false negatives 9, true negatives 141. What is the NPV (nearest value among the options)? Select TWO correct statements.

Select all that apply.

8. A journal club reviews a headache red-flag score versus imaging abnormality. The 2×2 counts are true positives 31, false positives 19, false negatives 9, true negatives 141. What is the NPV (nearest value among the options)?

9. A journal club reviews sweat chloride versus CF diagnosis. The 2×2 counts are true positives 8, false positives 12, false negatives 2, true negatives 178. What is the sensitivity (nearest value among the options)?

10. A journal club reviews a child fever traffic-light red versus serious bacterial infection. The 2×2 counts are true positives 16, false positives 24, false negatives 4, true negatives 156. What is the PPV (nearest value among the options)? Select TWO correct statements.

Select all that apply.